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# Dotplot with annotated sequences

If sequences in a dotplot have been annotated, the `dotplot()` method returns an `AnnotatedDrawable`.

## Reloading sequences and annotations

The data file, `tp53-annotations.json`, was created from a query of Ensembl for one-to-one orthologs of human TP53 between Human, Macaque, Orangutan and Marmoset. The resulting sequences were annotated with the location of the CDS for the canonical transcript, then the `annotation_db` was saved as json using `annotation_db.to_json()`.

## Removing annotation tracks

Thus we could remove the left annotation track, for instance with