:term:`USE_SPACE_GROUP <USE_SPACE_GROUP (LIBFRAG)>`
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      Should we exploit space group symmetry on your molecule? * For systems that are periodic lattices setting this value * to true will lead to large computational savings; however, * it does disable some cost saving tricks, such as better * initial guesses because I no longer necessarily have all * the fragments. Hence only set this to true if you know * for a fact that your system has space group symmetry.

      * **Type**: :ref:`boolean <op_c_boolean>`
      * **Default**: false

