>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
----------------------------------------MNG-----------------
TE--GDNFYVP-----FSNKTGLARSPYEYPQY---------------YLAEPWK-----
----YSALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-F
TVTMYTSMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGN-FR
FGNTHAIMGVAFTWIMALAC-AAPPLVG-W-----SRYIPEGMQCSCGPDYYTLNPNFNN
ESYVVYMFVVHFLVPFVIIFFCYGRLLCTV----KEAAAAQQ------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------ESASTQK------AEKEVTRMVVLMVIGFLVCWVPYASVAFYI
FTHQGS---DFGATFMTLPAFFAKSSALYNPVIYILMNKQFRNCMITTLCC--------G
KNPLGDDE--SGASTSKTEVSSVS-TSPVSPA----------------------------
------------------------------------------------------------
-
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
----------------------------------------MNG-----------------
TE--GPNFYVP-----FSNITGVVRSPFEQPQY---------------YLAEPWQ-----
----FSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-F
TTTLYTSLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSN-FR
FGENHAIMGVAFTWVMALAC-AAPPLVG-W-----SRYIPEGMQCSCGIDYYTLKPEVNN
ESFVIYMFVVHFTIPMIVIFFCYGQLVFTV----KEAAAQQQ------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------ESATTQK------AEKEVTRMVIIMVIFFLICWLPYASVAMYI
FTHQGS---NFGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLCC--------G
KNPLGDDE--ASATASKTE------TSQVAPA----------------------------
------------------------------------------------------------
-
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
----------------------------------------MNG-----------------
TE--GINFYVP-----MSNKTGVVRSPFEYPQY---------------YLAEPWK-----
----YRLVCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-F
TVTFYTAWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGN-FR
FSATHAMMGIAFTWVMAFSC-AAPPLFG-W-----SRYMPEGMQCSCGPDYYTHNPDYHN
ESYVLYMFVIHFIIPVVVIFFSYGRLICKV----REAAAQQQ------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------ESATTQK------AEKEVTRMVILMVLGFMLAWTPYAVVAFWI
FTNKGA---DFTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTICC--------G
KNPFGDEDVSSTVSQSKTEVSSVS-SSQVSPA----------------------------
------------------------------------------------------------
-
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
----------------------------------------MNG-----------------
TE--GKNFYVP-----MSNRTGLVRSPFEYPQY---------------YLAEPWQ-----
----FKILALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-F
TVTFYTAIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FK
FSSSHAFAGIAFTWVMALAC-AAPPLFG-W-----SRYIPEGMQCSCGPDYYTLNPDYNN
ESYVIYMFVCHFILPVAVIFFTYGRLVCTV----KAAAAQQQ------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------DSASTQK------AEREVTKMVILMVFGFLIAWTPYATVAAWI
FFNKGA---DFSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIFC--------G
KNPLGDDE-SSTVSTSKTEVSS------VSPA----------------------------
------------------------------------------------------------
-
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
----------------------------------------MNG-----------------
TE--GNNFYVP-----LSNRTGLVRSPFEYPQY---------------YLAEPWQ-----
----FKLLAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-F
TVTFYTAIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FK
FSSTHASAGIAFTWVMAMAC-AAPPLVG-W-----SRYIPEGIQCSCGPDYYTLNPEYNN
ESYVLYMFICHFILPVTIIFFTYGRLVCTV----KAAAAQQQ------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------DSASTQK------AEREVTKMVILMVLGFLVAWTPYATVAAWI
FFNKGA---AFSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLFC--------G
KNPLGDEE-SSTVSTSKTEVSS------VSPA----------------------------
------------------------------------------------------------
-
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
----------------------------------------MKQ-----------------
VPEFHEDFYIPI-PLDINNLS--AYSPFLVPQD---------------HLGNQGI-----
----FMAMSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-S
PLSFYSFFN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGN-FT
FKTPHAIAGCILPWISALAA-SLPPLFG-W-----SRYIPEGLQCSCGPDWYTTNNKYNN
ESYVMFLFCFCFAVPFGTIVFCYGQLLITL----KLAAKAQA------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------DSASTQK------AEREVTKMVVVMVLGFLVCWAPYASFSLWI
VSHRGE---EFDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSCMM-KMVC--------G
KN-IEEDE--ASTSSQVTQVSS------VAPEK---------------------------
------------------------------------------------------------
-
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
----------------------------------------MRK-----------------
MS--EEEFYL------FKNIS--SVGPWDGPQY---------------HIAPVWA-----
----FYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-V
FPVFVASCN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGN-FR
FSSKHALTVVLATWTIGIGV-SIPPFFG-W-----SRFIPEGLQCSCGPDWYTVGTKYRS
ESYTWFLFIFCFIVPLSLICFSYTQLLRAL----KAVAAQQQ------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------ESATTQK------AEREVSRMVVVMVGSFCVCYVPYAAFAMYM
VNNRNH---GLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIM-KMVC--------G
KA-MTDES--DTCSSQKTEVSTVS-STQVGPN----------------------------
------------------------------------------------------------
-
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------DLAETVIA-S
TISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VR
FDAKLAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGV
QSYMIVLMVTCCITPLSIIVLCYLQVWLAI----RAVAKQQK------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------ESESTQK------AEKEVTRMVVVMVLAFC-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
----------------------------------------MAQQWSLQRLAGRHPQDSYE
DSTQSSIFTYTN--------SNSTRGPFEGPNY---------------HIAPRWV-----
----YHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-S
TISVVNQVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGN-VR
FDAKLAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGV
QSYMIVLMVTCCITPLSIIVLCYLQVWLAI----RAVAKQQK------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------ESESTQK------AEKEVTRMVVVMVLAFCFCWGPYAFFACFA
AANPGY---PFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLF----------G
KK-VDDGS--ELSSASKTEVSSV---SSVSPA----------------------------
------------------------------------------------------------
-
>    10== Z68193   1 human Red Opsin <>[]
----------------------------------------MAQQWSLQRLAGRHPQDSYE
DSTQSSIFTYTN--------SNSTRGPFEGPNY---------------HIAPRWV-----
----YHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-S
TISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VR
FDAKLAIVGIAFSWIWSAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGV
QSYMIVLMVTCCIIPLAIIMLCYLQVWLAI----RAVAKQQK------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------ESESTQK------AEKEVTRMVVVMIFAYCVCWGPYTFFACFA
AANPGY---AFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLF----------G
KK-VDDGS--ELSSASKTEVSSV---SSVSPA----------------------------
------------------------------------------------------------
-
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
----------------------------------------MTEAWNVAVFAARRSRDD-D
DTTRGSVFTYTN--------TNNTRGPFEGPNY---------------HIAPRWV-----
----YNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-S
TISVFNQIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGN-IK
FDSKLAIIGIVFSWVWAWGW-SAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSVELGC
QSFMLTLMITCCFLPLFIIIVCYLQVWMAI----RAVAAQQK------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------ESESTQK------AEREVSRMVVVMIVAFCICWGPYASFVSFA
AANPGY---AFHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNCIMQLF----------G
KK-VDDGS--EASTTSRTEVSSVS-NSSVAPA----------------------------
------------------------------------------------------------
-
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
----------------------------------------MAA-WEAA-FAARRRHEE-E
DTTRDSVFTYTN--------SNNTRGPFEGPNY---------------HIAPRWV-----
----YNLTSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-S
TISVINQIS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGN-IK
FDGKLAVAGILFSWLWSCAW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSDPGV
QSYMVVLMVTCCFFPLAIIILCYLQVWLAI----RAVAAQQK------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------ESESTQK------AEKEVSRMVVVMIVAYCFCWGPYTFFACFA
AANPGY---AFHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNCILQLF----------G
KK-VDDGS--EVST-SRTEVSSVS-NSSVSPA----------------------------
------------------------------------------------------------
-
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
----------------------------------------MSS-----------------
----NSSQAPPN-G---------TPGPFDGPQWP--------------YQAPQST-----
----YVGVAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-S
SVSLSNNIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGD-FQ
FQRRHAVSGCAFTWGWALLW-SAPPLLG-W-----SSYVPEGLRTSCGPNWYTGGS--NN
NSYILSLFVTCFVLPLSLILFSYTNLLLTL----RAAAAQQK------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------EADTTQR------AEREVTRMVIVMVMAFLLCWLPYSTFALVV
ATHKGI---IIQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSCLLEMLCC--------G
YQPQRTGKASPGTPGPHADVTAAGLRNKVMPAH---------------------------
----------------------------------------PV------------------
-
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
----------MESGN-----VS--------SSLFGNVSTALRP-----------------
EARLSAE-----------TRLLGWNVPPEELR----------------HIPEHWLTYPEP
PESMNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--T
PIFIYNSFH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--K
MTHGKAIAMIIFIYMYATPW-VVACYTETW-----GRFVPEGYLTSCTFDYLT--DNFDT
RLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKK-----------------
----------------------------------------------------------MN
-----------VESL---------------------------------------------
--------------RSNVDKNKET------AEIRIAKAAITICFLFFCSWTPYGVMSLIG
AFGDKT---LLTPGATMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLAL------
---NEKAP--ESSAVASTSTTQEP--QQTTAA----------------------------
------------------------------------------------------------
-
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
----------MEYHN-----VS---------SVLGNVSSVLRP-----------------
DARLSAE-----------SRLLGWNVPPDELR----------------HIPEHWLIYPEP
PESMNYLLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--T
PIFIYNSFH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--K
MTHGKAIAMIIFIYLYATPW-VVACYTESW-----GRFVPEGYLTSCTFDYLT--DNFDT
RLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKK-----------------
----------------------------------------------------------MN
-----------VDSL---------------------------------------------
--------------RSNVDKSKEA------AEIRIAKAAITICFLFFASWTPYGVMSLIG
AFGDKT---LLTPGATMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPWLAI------
---SEKAP--ESRAAISTSTTQEQ--QQTTAA----------------------------
------------------------------------------------------------
-
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
----------ME-------------------PLCNASEPPLRP-----------------
EARSSGN---------GDLQFLGWNVPPDQIQ----------------YIPEHWLTQLEP
PASMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--A
PIF--NSFH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--N
MTFTKAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFDT
RLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKK-----------------
----------------------------------------------------------MN
-----------VESL---------------------------------------------
--------------RSNVDKSKET------AEIRIAKAAITICFLFFVSWTPYGVMSLIG
AFGDKS---LLTQGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLGV------
---NEKSG--EISSAQSTTTQEQ---QQTTAA----------------------------
------------------------------------------------------------
-
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
----------MD-------------------ALCNASEPPLRP-----------------
EARMSSG--------SDELQFLGWNVPPDQIQ----------------YIPEHWLTQLEP
PASMHYMLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--A
PIFIYNSFH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--N
MTFTKAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFDT
RLFVGTIFLFSFVVPTLMILYYYSQIVGHVFNHEKALREQAKK-----------------
----------------------------------------------------------MN
-----------VESL---------------------------------------------
--------------RSNVDKSKET------AEIRIAKAAITICFLFFVSWTPYGVMSLIG
AFGDKS---LLTPGATMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPWLGV------
---NEKSG--EASSAQSTTTQEQT--QQTSAA----------------------------
------------------------------------------------------------
-
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
--------------------------------MTNATGPQMAY-----------------
YGAASMDFGYP------EGVSIVDFVRPEIKP----------------YVHQHWYNYPPV
NPMWHYLLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-V
PFFTYNCFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNG-PK
LTTGKAVVFALISWVIAIGC-ALPPFFG-W-----GNYILEGILDSCSYDYLT--QDFNT
FSYNIFIFVFDYFLPAAIIVFSYVFIVKAIFAHEAAMRAQAKK-----------------
----------------------------------------------------------MN
-----------VSTL---------------------------------------------
--------------RS-NEADAQR------AEIRIAKTALVNVSLWFICWTPYALISLKG
VMGDTS---GITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWFCV------
HE-TETKS--NDDSQSNSTVAQDK-A----------------------------------
------------------------------------------------------------
-
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
--------------------------------MANVTGPQMAF-----------------
YGSGAATFGYP------EGMTVADFVPDRVKH----------------MVLDHWYNYPPV
NPMWHYLLGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-F
PPFCYNCFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNG-PK
LTQGKATFMCGLAWVISVGW-SLPPFFG-W-----GSYTLEGILDSCSYDYFT--RDMNT
ITYNICIFIFDFFLPASVIVFSYVFIVKAIFAHEAAMRAQAKK-----------------
----------------------------------------------------------MN
-----------VTNL---------------------------------------------
--------------RS-NEAETQR------AEIRIAKTALVNVSLWFICWTPYAAITIQG
LLGNAE---GITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWFCV------
HE-KDPND--VEENQSSNTQTQEK-S----------------------------------
------------------------------------------------------------
-
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
----------MESF----------------AVAAAQLGPHFAP-----------------
LS----------------NGSVVDKVTPDMAH----------------LISPYWNQFPAM
DPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-T
PMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RP
MTIPLALGKM---------------------------YVPEGNLTSCGIDYLE--RDWNP
RSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK-----------------
----------------------------------------------------------MN
-----------VKSL---------------------------------------------
--------------RS-SEDAEKS------AEGKLAKVALVTITLWFMAWTPYLVINCMG
LFKF-E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------
GK-VDDGK--SSDAQSQA-TASEA-ESKA-------------------------------
------------------------------------------------------------
-
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
----------MESF----------------AVAAAQLGPHFAP-----------------
LS----------------NGSVVDKVTPDMAH----------------LISPYWNQFPAM
DPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-T
PMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RP
MTIPLALGKIAYIWFMSSIW-CLAPAFG-W-----SRYVPEGNLTSCGIDYLE--RDWNP
RSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK-----------------
----------------------------------------------------------MN
-----------VKSL---------------------------------------------
--------------RS-SEDAEKS------AEGKLAKVALVTITLWFMAWTPYLVINCMG
LFKF-E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------
GK-VDDGK--SSDAQSQA-TASEA-ESKA-------------------------------
------------------------------------------------------------
-
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
----------MDSF----------------AAVATQLGPQFAA-----------------
PS----------------NGSVVDKVTPDMAH----------------LISPYWDQFPAM
DPIWAKILTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-T
PMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RP
MTIPLALGKIAYIWFMSTIWCCLAPVFG-W-----SRYVPEGNLTSCGIDYLE--RDWNP
RSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK-----------------
----------------------------------------------------------MN
-----------VKSL---------------------------------------------
--------------RS-SEDADKS------AEGKLAKVALVTISLWFMAWTPYLVINCMG
LFKF-E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------
GK-VDDGK--SSEAQSQA-TTSEA-ESKA-------------------------------
------------------------------------------------------------
-
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
MER-----SHLPET----------------PFDLAHSGPRFQA-----------------
QSSG--------------NGSVLDNVLPDMAH----------------LVNPYWSRFAPM
DPMMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-S
PVMIINFYY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGING-TP
MTIKTSIMKILFIWMMAVFW-TVMPLIG-W-----SAYVPEGNLTACSIDYMT--RMWNP
RSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKK-----------------
----------------------------------------------------------MN
-----------VKSL---------------------------------------------
--------------RS-SEDCDKS------AEGKLAKVALTTISLWFMAWTPYLVICYFG
LFKI-D---GLTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCVF------
GN-TDEPK--PDAPASDTETTSEA-DSKA-------------------------------
------------------------------------------------------------
-
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
MER-----SLLPEP----------------PLAMALLGPRFEA-----------------
QTGG--------------NRSVLDNVLPDMAP----------------LVNPHWSRFAPM
DPTMSKILGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-S
PVMIINFYY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGING-TP
MTIKTSIMKIAFIWMMAVFW-TIMPLIG-W-----SSYVPEGNLTACSIDYMT--RQWNP
RSYLITYSLFVYYTPLFMICYSYWFIIATVAAHEKAMRDQAKK-----------------
----------------------------------------------------------MN
-----------VKSL---------------------------------------------
--------------RS-SEDCDKS------AENKLAKVALTTISLWFMAWTPYLIICYFG
LFKI-D---GLTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMCVC------
GT-TDEPK--PDAPPSDTETTSEA-ESKD-------------------------------
------------------------------------------------------------
-
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
--------------------------------MIAVSGPSYEA-----------------
FSYGGQA--------RFNNQTVVDKVPPDMLH----------------LIDANWYQYPPL
NPMWHGILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-S
PPMVINCYY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSG-KP
LSINGALIRIIAIWLFSLGW-TIAPMFG-W-----NRYVPEGNMTACGTDYFN--RGLLS
ASYLVCYGIWVYFVPLFLIIYSYWFIIQAVAAHEKNMREQAKK-----------------
----------------------------------------------------------MN
-----------VASL---------------------------------------------
--------------RS-SENQNTS------AECKLAKVALMTISLWFMAWTPYLVINFSG
IFNL-V---KISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPSLAC------
-A-AEPSS--DAVSTTSGTTTVTD-NEKSNA-----------------------------
------------------------------------------------------------
-
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
MAN---------------------------QLSYSSLGWPYQP-----------------
------------------NASVVDTMPKEMLY----------------MIHEHWYAFPPM
NPLWYSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-M
PTMTSNCFA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAA-AP
LTHKKATLLLLFVWIWSGGW-TILPFFG-W-----SRYVPEGNLTSCTVDYLT--KDWSS
ASYVVIYGLAVYFLPLITMIYCYFFIVHAVAEHEKQLREQAKK-----------------
----------------------------------------------------------MN
-----------VASL---------------------------------------------
--------------RANADQQKQS------AECRLAKVAMMTVGLWFMAWTPYLIISWAG
VFSSGT---RLTPLATIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSLAC------
GS-GESGS--DVKSEASATTTMEE-KPKIPEA----------------------------
------------------------------------------------------------
-
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
---------------------------------------MVES-----------------
TTLVNQTWWY--------NPTVD--------------------------IHPHWAKFDPI
PDAVYYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGF
PLKTISAFM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKK
MSHRRAFLMIIFVWMWSIVW-SVGPVFN-W-----GAYVPEGILTSCSFDYLS--TDPST
RSFILCMYFCGFMLPIIIIAFCYFNIVMSVSNHEKEMAAMAKR-----------------
----------------------------------------------------------LN
-----------AKEL---------------------------------------------
--------------R--KAQAGAS------AEMKLAKISMVIITQFMLSWSPYAIIALLA
QFGPAE---WVTPYAAELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDE
KE-CEDAN--DAEEEVVASER--G-GESRDAAQMKEMMAMMQKMQAQQAAYQPPPPPQGY
--PPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQAYQ
A
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
----------------------------------------MGR-----------------
DLRDNETWWY--------NPSIV--------------------------VHPHWREFDQV
PDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGF
PLMTISCFL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKK
MSHRRAFIMIIFVWLWSVLW-AIGPIFG-W-----GAYTLEGVLCNCSFDYIS--RDSTT
RSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKR-----------------
----------------------------------------------------------LN
-----------AKEL---------------------------------------------
--------------R--KAQAGAN------AEMRLAKISIVIVSQFLLSWSPYAVVALLA
QFGPLE---WVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDD
KE-TEDDK--DAETEIPAGESSDA-APSADAAQMKEMMAMMQKMQQQQAAY----PPQGY
APPPQGYPPQGY--PPQGYPPQGYPPQGYPP---PPQGAPPQ-GAPPAAPPQGVDNQAYQ
A
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
M---------MDVNSSGRPDLYGHLRSFL-LPEVGRGLPDLSPDG---------------
GADPVAGSWAPHLLS---EVTASPAPTWDAPPDNASGCGEQINYGRVE------------
----KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-M
PFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVR
QNGKCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF---------
-GYTIYSTAVAFYIPMSVMLFMYYQIY-------KAARKSAAKHKF--------------
-------------------PGF-----------------PRVE---------PDSVIALN
G----------IVKLQK--------------------------EVEECAN----------
--------LSRLLKHERKNISIFK------REQKAATTLGIIVGAFTVCWLPFFLLSTAR
PFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYR---NIN
RK-LSAAGMHEALKLAERPERPEFVLQNADYCRKK-------------------------
----------------------------------------------------GHDS----
-
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
M-----------------------------------------------------------
----------PHLLSGFLEVTASPAPTWDAPPDNVSGCGEQINYGRVE------------
----KVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-M
PFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVR
QNGKCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF---------
-GYTIYSTAVAFYIPMSVMLFMYYQIY-------KAARKSAAKHKF--------------
-------------------PGF-----------------PRVQ---------PESVISLN
G----------VVKLQK--------------------------EVEECAN----------
--------LSRLLKHERKNISIFK------REQKAATTLGIIVGAFTVCWLPFFLLSTAR
PFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTSRSLLQCQYR---NIN
RK-LSAAGMHEALKLAERPERSEFVLQNSDHCGKK-------------------------
----------------------------------------------------GHDT----
-
>    31=p A47425 serotonin receptor 5HT-7 - rat
M-----------------------------------------------------------
----------PHLLSGFLEVTASPAPTWDAPPDNVSGCGEQINYGRVE------------
----KVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-M
PFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVR
QNGKCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF---------
-GYTIYSTAVAFYIPMSVMLFMYYQIY-------KAARKSAAKHKF--------------
-------------------PGF-----------------PRVQ---------PESVISLN
G----------VVKLQK--------------------------EVEECAN----------
--------LSRLLKHERKNISIFK------REQKAATTLGIIVGAFTVCWLPFFLLSTAR
PFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYR---NIN
RK-LSAAGMHEALKLAERPERSEFVLQNSDHCGKK-------------------------
----------------------------------------------------GHDT----
-
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
MDVLSPGQ--------------G-------------------------------------
------------------NNTTSPPAPFETGGNTT-------------GISDVTVSY---
----QVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-L
PMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNK
RTPRRAAALISLTWLIGFLI-SIPPMLG-WRTPE-DRSDPDA--CTISKDH---------
-GYTIYSTFGAFYIPLLLMLVLYGRIF-------RAARFRIRK-----------------
----------------------TVKKVEKTGADTRHGASPAPQ---------PKKS--VN
GESGSRNWRLGVESK-----AGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSE
AG--PTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVL
PFCESSC--HMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC------
RQ----------------------------------------------------------
------------------------------------------------------------
-
>    33=p A35181 serotonin receptor class 1A - rat
MDVFSFGQ--------------G-------------------------------------
------------------NNTTASQEPFGTGGNVT-------------SISDVTFSY---
----QVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-L
PMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNK
RTPRRAAALISLTWLIGFLI-SIPPMLG-WRTPE-DRSDPDA--CTISKDH---------
-GYTIYSTFGAFYIPLLLMLVLYGRIF-------RAARFRIRK-----------------
----------------------TVRKVEKKGAGTSLGTSSAPP---------PKKS--LN
GQPGSGDWRRCAENR-----AVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSE
SG--SNSYAPACLERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVL
PFCESSC--HMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC------
RR----------------------------------------------------------
------------------------------------------------------------
-
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
MANFTFGDLALDVAR-----MGGLASTPSGLRSTGLTTPGLSPTGL-------------V
TSDFNDSYGLTG---QFINGSHSSRSRDNASANDTSATN---------MTDDRYWSLTVY
SHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-M
PLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRR
RSARRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK---------
-GYTIFSTVGAFYLPMLVMMIIYIRIW-------LVARSRIRKDKFQMTKARLKTEETTL
VASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVN
SNSSS------SERL----KQIQIETAEAFANGCAEEASIAMLERQ-CNNGKKISSNDTP
YS------------RT-REKLELK------RERKAARTLAIITGAFLICWLPFFIIALIG
PFVDPE---GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYR----RG
HR----------------------------------------------------------
------------------------------------------------------------
-
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
MANFTFGDLALDVAR-----MGGLASTPSGLRSTGLTTPGLSPTGL-------------V
TSDFNDSYGLTG---QFINGSHSSRSRDNASANDTSATN---------MTDDRYWSLTVY
SHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-M
PLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRR
RSARRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK---------
-GYTIFSTVGAFYLPMLVMMIIYIRIW-------LVARSRIRKDKFQMTKARLKTEETTL
VASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVN
SNSSS------SERL----KQIQIETAEAFANGCAEEASIAMLERQ-CNNGKKISSNDTP
YS------------RT-REKLELK------RERKAARTLAIITGAFLICWLPFFIIALIG
PFVDPE---GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYR----RG
HR----------------------------------------------------------
------------------------------------------------------------
-
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
MEGAE-GQEELDWEA-----LY--LRLP--LQNCSWNSTGWEPNWN-------------V
TVVPNTTWWQ-------------ASAPFDTPAALVR------------------------
----AAAKAVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-M
PLGAVYEVV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHA
STAKRVGMMIACVWTVSFFV-CIAQLLG-WKDPDWNQRVSEDLRCVVSQDV---------
-GYQIFATASSFYVPVLIILILYWRIY-------QTARKRIRR-----------------
----------------------------RRGATARGGVGPPPV---------PAGGALVA
GGGSGGIAAAVVAVIGRPLPTISETTTTGFTNVSSNNTSP---EKQSCANGLEADPPTTG
YGAVAAAYYPSLVRRKPKEAADSK------RERKAAKTLAIITGAFVACWLPFFVLAILV
PTCDCE----VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLLCGRRV----RR
RR----------------------------------------------------------
---------------------------------------APQ------------------
-
